The Trafford Wharfside Development Framework has been prepared by the council in discussion with major landowning partners including Peel, Manchester United and Salford city council.
Town hall bosses say the public will be given the opportunity to air their views on the strategy in a consultation due to be launched in the near future.
They say the plan has identified a number of potential development sites and will be used to set an overall strategy to guide future, well-designed development in the area.
The masterplan places nature and landscape at the heart of its vision, celebrates the Manchester Ship Canal waterfront and the Imperial War Museum, creates opportunities for up to 5,000 high-quality new homes, connects Trafford Wharfside to the city centre and develops a high-quality setting for Manchester United as they develop their plans for a world-class football stadium.
The report on the draft Trafford Wharfside masterplan will be discussed by Trafford councillors at its executive meeting on February 21.